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Hence, according to precautionary principle any condition potentially leading to further depletion of GSH stores should be carefully avoided

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In other words, no harmful interactions are known at normal doses

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4%), the longer incubation time (24 h vs

Receptor autophosphorylation, downstream phosphorylation of IRS-1 and Shc, and activation of PI3K and MAPK occur with similar kinetics to native IGF-1 once the ligand reaches the receptor