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These modalities enhance GLP-1 sensitivity , preserve lean muscle mass , and reduce inflammation and visceral fat (fat around the organs (especially belly)a synergy shown to amplify metabolic benefits (PMC)
But a year later investigators failed to reproduce their results which dampened enthusiasm to go any further (Moore
Bottom line Semaglutide starts working soon after you take it, but noticeable effects like weight loss or better blood sugar control may take weeks to months to appear
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