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Neuroinflammation is the normal response of the CNS to various insults, such as tissue damage, infection, autoimmune diseases, and epilepsy, and can balance the stronger metabolic needs during increased neuronal activity (131, 132)
doi: 10.1080/10408398.2021.1884840 58
Chronic OS also activates TGF- /Smad and PI3K-Akt pathways (102104), promoting epithelialmesenchymal transition (EMT) and fibroblast activation, thereby contributing to pulmonary fibrosis, as evidenced in NdO animal studies (97, 105) (see Figure 3)
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(PubMed) Meplan C, Hesketh J
Scientifically, that line leans more into metabolic efficiency and blood-flow support
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