gastroprotective, protects the gut
It has become a promising neuroprotective agent not only in PD and AD but also in other neurodegenerative diseases, including ALS, stroke and MS (Fig
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The peptides under investigation, include: Nle-AngIV (Nle-Tyr-Ile-His-Pro-Phe) and its analogs such as D-Nle-YIH, acetyl-NleYIH, -amino butyric acid-YIH, NleYI-amide, and the primary focus, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide (Dihexa)
These detrimental effects are linked to suppression of the Nrf2 antioxidant pathway
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