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Alterations in xenobiotic metabolism in the long-lived Little mice

As the SnCE1 tetramer formation is structurally incompatible with SUMO1 binding at S1, we hypothesize Lys231-acetylation of SnCE1 promoting its deSUMOylase activity by stabilization of the SnCE1 monomeric state (Fig

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We walk through the biology that makes GLP-1RAs a plausible therapeutic in HS, the study's contributions, and the important questions that prospective studies will still need to answer

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Severe case of melanosis coli, developed secondary to the use of anthroquinone laxatives sold as herbal supplements