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Decreased levels of TNF- and IL-6 indicate that NNMT inhibition not only modulates metabolism but also improves the inflammatory microenvironment, a key component in metabolic disease development and insulin resistance

Improved Glucose and Lipid Metabolism : Experimental studies demonstrate that suppression of NNMT activity with 5-Amino-1MQ correlates with improved glucose tolerance and reduced hepatic lipid accumulation

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