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The glucagon-like peptide 1 analogue, exendin-4, attenuates the rewarding properties of psychostimulant drugs in mice

Recommended replacement wording is: How is this compound combination evaluated in laboratory peptide signaling studies? Replace this question with: What signaling behavior has been observed in experimental models? The answer should summarize published experimental observations, monitored pathway activity, and model specific signal duration findings using neutral language

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In both cases, bound-form glutathione must be converted to reduced-form glutathione or cysteine on or in the hepatocytes

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