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Cristodoro, M., Zambella, E., Fietta, I., Inversetti, A
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Dalmasso and colleagues (Gastroenterology, 2008, PMID 18061177) reported that KPV is taken up through the di- and tripeptide transporter PepT1, which is normally expressed in the small intestine and induced in the colon during inflammation, and that uptake was associated with reduced NF-B activation in human epithelial and immune cell lines
Biosynthesis and biotransformation of glutathione S-conjugates to toxic metabolites
Results NAFLD development was associated with TNF overproduction and perturbation of glutathione homeostasis in the liver Long-term HFD consumption in mice represents a well-established animal model of NAFLD