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The incubation of solutions of GSH without the metal complex did not show any conversion to GSSG (Supplementary Fig

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GGT1, a member of the GGT family, has been shown to inhibit ferroptosis via the GSH/GPX4 axis and thus inhibit tumour progression [6, 29], and its amino acid sequence shares 34% homology with its fellow family member GGT7, the protein space structure also has similarity

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In 3T3-L1 adipocyte cell models, 5-Amino-1MQ at 30 M concentration produced significant reductions in intracellular 1-MNA levels, confirming target engagement

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The results demonstrated that these flavonoids induced concentration-dependent vasorelaxation in endothelium-intact aortic rings, an effect diminished when the endothelium was removed

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