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2021;137(6):e12844
Semaglutide is intentionally started at a low dose and gradually increased over several weeks to months, allowing the gastrointestinal system time to adapt
An important point for the first month: this phase is about tolerance and foundation-building, not dramatic transformation
The Myers cocktail IV is very safe and generally well tolerated
Therefore, prescribing it for weight loss is considered off-label
For that reason, dose strategy should consider systemic hormonal status rather than symptom relief alone
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