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Cardinal symptoms of gastroparesis include persistent nausea, recurrent vomiting (particularly of undigested food consumed hours earlier), early satiety, postprandial fullness, bloating, and upper abdominal discomfort

Feinfeld, D

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Collectively, these findings suggest that TRIM37 can ubiquitinate TRIM28 and that this ubiquitination requires the MATH domain-mediated TRIM37TRIM28 interaction

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This may be beneficial to patients experiencing nausea from medications that slow stomach emptying, including GLP-1 drugs