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Water molecules facilitate nucleophilic attack on the carbonyl carbon of the peptide bond, a process accelerated exponentially by temperature increases above 8C

25 Metabolic bariatric surgery has benefits beyond weight loss, with strong evidence that it reverses T2DM and significantly reduces the risk of major CVD outcomes, including coronary artery disease, myocardial infarction, cerebrovascular accident, heart failure, and CVD mortality

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RMB designed and reviewed critically the article