tirzepatide injection site bruise from semaglutide bruising? : r/Ozempic Bruising after injections can be – Does therapy shot cause bruising?

Lancet Diabetes Endocrinol (2022) 10(6):393406

Research shows injectable semaglutide remains stable for 56 days once opened

Ingredients Ingredients: Filler: mannitol (may have a laxative effect if consumed in excess!)

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Key Takeaways Tirzepatide vs semaglutide comes down to dual agonist vs single agonist: tirzepatide targets both GLP-1 and GIP receptors, while semaglutide targets GLP-1 alone The only head-to-head trial (SURPASS-2) found tirzepatide superior to semaglutide for both blood sugar control and weight loss In separate obesity trials, tirzepatide 15mg achieved 20.9% weight loss at 72 weeks vs semaglutide 2.4mg's 14.9% at 68 weeks Semaglutide has proven cardiovascular benefit (SELECT trial: 20% MACE reduction)

For us, this is a brand-new tool in our toolbox to benefit the quality of life in these patients." While GLP-1s are being seen as the hearts newest best friend, on the flip side, obesity is one of its worst enemies