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Hepatic fat accumulation results from an imbalance between lipid acquisition and lipid disposal, which are regulated through four major pathways: uptake of circulating lipids, de novo lipogenesis (DNL), fatty acid oxidation (FAO), and export of lipids in very low-density lipoproteins (VLDL) (Fig

Some alternatives are FDA-approved for weight loss and management

Wegovy should not be used during pregnancy or breastfeeding, and effective contraception is recommended for women of childbearing potential

A healthcare provider can recommend dietary modifications, portion control strategies, and meal timing

It is mainly present in muscle tissue and in the heart, as well as in nerve tissue

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