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[1] However, emerging research and anecdotal evidence suggest that die-off may be more common than previously thought and may occur in patients with other conditions too, such as candidiasis/yeast overgrowth, other bacterial, fungal or parasitic infections, and SIBO
doi: 10.1111/dom.14232 26 ArodaVRBainSCCariouBPiletiMRoseLAxelsenMet al
The patients who maintained the most weight loss shared common traits: they had made significant dietary changes , increased physical activity, and often used a structured tapering approach rather than stopping abruptly
ii) Cardiovascular death: Excluding the SOUL trial strengthened the effect (shifting from non-significant to significant), suggesting sensitivity to SOUL but moderate robustness due to consistent overall effect direction and magnitude
More importantly, it was estimated that approximately 45% of HFpEF patients had DM
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