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It is important to understand that immediate hypersensitivity reactions typically occur after prior sensitisation

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Placebo-Controlled and Randomized Controlled Trial Design Retatrutides key obesity, type 2 diabetes, and MASLD studies used randomized, double-blind, placebo-controlled designs, which help reduce bias compared with uncontrolled case reports or anecdotal reports [4], [5], [6], [8]

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