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Reconstituted: Store refrigerated (28C) and use within approximately 4 weeks

Because of this evidence, a connection has been suggested between the activation of the hypothalamus-pituitary-adrenal (HPA) axis and the stress inhibition of the hypothalamus-pituitary-gonadal (HPG) axis [9]

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A systematic review and meta-analysis found that creatine supplementation was associated with a small but statistically significant increase in serum creatinine of approximately 0.07 micromol/L