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It will also be important to determine whether these drugs can be used in combination with other therapies to optimize the treatment of HFpEF in obese patients, while minimizing side effects and drug interactions

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For example, pregnancy or planning to become pregnant often requires stopping the medication, and certain surgeries may mean pausing it temporarily

Retatrutide is an investigational triple receptor agonist that simultaneously targets three hormone receptors: glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors

10.1080/17512433.2017.1253472 Expert

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