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Consistent with this, Bloom et al
Genetics, pathophysiology, diagnosis, treatment, management, and prevention of migraine
In this model, NO-related modulation may influence endothelial function and local microvascular stability
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Cell Metabolism , 33 (5), 10131026.e6
For instance, a large network meta-analysis showed that SGLT-2 inhibitors reduced hospitalization for HF and renal composite outcome more than GLP-1RA [15], and that in patients with cardiovascular disease, SGLT-2 inhibitors show significant reduction in both heart failure (HF) hospitalizations and mortality for patients with HF and reduced ejection fraction [16]
