All compounds referenced in this article are for research use only
Common causes or triggers may include: Viral or bacterial infections including COVID-19, Lyme disease, Epstein-Barr virus (EBV), or pneumonia (5) Micronutrient deficiencies, including magnesium, vitamin D, and/or B vitamins (6) Existing autoimmune conditions including Hashimotos, Sjgrens, Celiac disease, or undiagnosed autoimmunity Mast cell activation, leading to histamine overload and systemic inflammation Connective tissue disorders including Ehlers-Danlos Syndrome (EDS) Toxin exposure including to mycotoxins from mold Chronic stress or unresolved trauma There are also different subtypes of POTS with different physiological causes: Neuropathic POTS: Caused by nerve dysfunction in the hands and feet (5,6) Hyperadrenergic POTS: Caused by too-high volumes of norepinephrine in the blood (5,7) Hypovolemic POTS: Caused by reduced blood volume (5) POTS and COVID-19 Does COVID cause POTS
Vitamin C helps "recharge" glutathione, and glutathione does the same for Vitamin C
This tipping point may convert localized damage into expanding tissue injury
Physical activity may alter the secretion of signaling proteins from skeletal muscles [20]
Jones, N