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Source Data Extended Data Fig./Table 1 (download XLSX Statistical source data

For example, cardiovascular outcomes trials have already shown that GLP-1 drugs reduce major heart events in people with diabetes and obesity

AOD-9604 and Tesamorelin in Combination Research The theoretical basis for discussing AOD-9604 alongside Tesamorelin comes from their non-overlapping mechanisms: AOD-9604 acts locally on fat tissue without engaging the GH/IGF-1 axis, while Tesamorelin works upstream by stimulating pituitary GH release

Dihexa acts primarily through hepatocyte growth factor (HGF) signaling by potentiating HGF/c-Met receptor interaction

Despite advances in the understanding of its clinical features, effective treatments remain elusive, necessitating further exploration of the underlying mechanisms and novel therapeutic targets

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