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The reductions were most pronounced at a daily dose of 30 mL and were observed in both overweight/obese adults and those with T2DM

It also downregulates inflammatory cytokines and promotes the migration and differentiation of stem cells to sites of injury

Interestingly, DPP-4 inhibition does not have to take place systemically but only in the intestine as shown with oral administration of low doses of inhibitor (122)

One important limitation is that these dosing approaches are largely anecdotal and not derived from controlled psychiatric research

Ongoing surveillance is only recommended if extensive gastric atrophy, intestinal metaplasia, or additional risk factors are identified

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