Eur J Drug Metab Pharmacokinet (2006) 31(2):10916
That matters in chronic conditions, where treatment can last for months or even years
Possible monitoring points include injection site reactions, swelling, joint discomfort, muscle aches, numbness or tingling, blood sugar changes, or fluid retention
Reported side effects include mild drowsiness, headache, and injection site reactions
In line with this hypothesis, an observational study of 200 adults with type 1 diabetes demonstrated improvements in albuminuria and in eGFR with SGLT2i use over 12 months among adults with a baseline eGFR 7000 participants identified a 2.8-fold greater risk of DKA with SGLT2i use compared with placebo in adults with type 1 diabetes [44]
No as the body needs to absorb the single dose of B12 first