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Bupropions norepinephrinedopamine reuptake inhibition (NDRI) mechanism was chosen to counteract precisely that suppression ( Standard practice for a first moderate depressive episode is to see whether a single antidepressant works before combining two, so starting vortioxetine and bupropion together needs an explanation

If nausea occurs, eating smaller meals on injection day often helps regardless of injection time

The injections go straight into your bloodstream, meaning your body can use them right away

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