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It has been observed that intake of high content of phenolic compounds from olive oil (366 mg/kg) reduced the expression of CD40 ligand gene and its downstream products, and was associated with a decrease in oxidized LDL in plasma and an increase in urinary polyphenols (40)
Such nitration-dysfunction is specific to HGF among other major growth factors examined (FGF2, IGF1, and TGF-2), highlighting the inhibitory impact of accumulation of nitrated HGF on myogenic stem cell biology during aging 32
J Clin Transl Hepatol 2:153161
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PMCID: PMC3962576
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