Semaglutide was not mutagenic or clastogenic in a standard battery of genotoxicity tests (bacterial mutagenicity (Ames), human lymphocyte chromosome aberration, rat bone marrow micronucleus)
The SURMOUNT trials showed weight loss of up to 22.5% of body weight at the highest doses in people with obesity
Instead, it positioned the conduct as a deceptive trade practice affecting consumer safety
262-OR: Pemvidutide, a GLP-1/glucagon dual receptor agonist, in subjects with overweight or obesitya 48-week, placebo-controlled, phase 2 (MOMENTUM) trial
As semaglutide alters the way the body responds to food intake, it may inadvertently affect gallbladder function
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