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Since they were first identified as therapeutic agents in 2005, glucagon-like peptide-1 receptor agonists, or GLP-1s, have evolved into a medical breakthrough in diabetes management and its comorbidities
Dormandy JA, Charbonnel B, Eckland DJ, Erdmann E, Massi-Benedetti M, Moules IK, Skene AM, Tan MH, Lefebvre PJ, Murray GD, Standl E, Wilcox RG, Wilhelmsen L, Betteridge J, Birkeland K, Golay A, Heine RJ, Koranyi L, Laakso M, Mokan M, Norkus A, Pirags V, Podar T, Scheen A, Scherbaum W, Schernthaner G, Schmitz O, Skrha J, Smith U, Taton J, PROactive Investigators
Many early exposures result in healthy pregnancies, but discontinuation upon discovery is essential
Now, the reason these drugs have crossed into the chronic pain conversation is the emerging evidence that GLP-1 receptors dont just exist in the gut and pancreas
It is also what makes accurate dosing so important
