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Patients carrying certain alleles may experience faster or more robust semaglutide effects, while others may require longer titration or complementary approaches

See the handling matrix for full storage parameters

Conversely, the combined gastrointestinal effects may prove intolerable for some patients, with compounded nausea, diarrhoea, or constipation limiting the feasibility of concurrent use

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Clinical trials show reduced visceral fat, better body composition, and improved lipid profiles

Gradual dose escalation as prescribed by your healthcare provider allows your body to adapt to the medication