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Importantly, functional B12 deficiency can sometimes coexist with high total B12 levels, especially in kidney disease, and may require additional testing with methylmalonic acid (MMA) or holotranscobalamin if deficiency is suspected clinically
Metabolic Function Research Retas influence on glucose tolerance, insulin sensitivity, and lipid metabolism makes it a useful tool for exploring the hormonal and cellular pathways tied to type 2 diabetes, insulin resistance, and non-alcoholic fatty liver disease (NAFLD)
My personal experience of being told by some doctors I'm now sorted as B12 replete so no longer b12 deficient is incorrect
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Lineweaver-Burk plots were used to analyze these interactions, allowing for the determination of the inhibition type (e.g., competitive, non-competitive, or mixed) and the Ki values for each compound
