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Introduction Neurobehavioral and metabolic effects of GLP-1 RAs How GLP-1 RAs affect appetite Changes in cravings, mood, and behavior How GLP-1 drugs may reshape addiction pathways Clinical and public health implications Conclusions References Further reading The widely used obesity and diabetes GLP-1 drugs may do far more than reduce weight
ScienceDirect Hsu, Y.-T., & Miller, W
Why Normal Methods Fail Calorie restriction triggers a survival response
Boxes for the GLP-1 medications Wegovy (semaglutide) and Zepbound (tirzepatide) pictured in California, May 8, 2025
Wider access to these drugs can improve metabolic health outcomes, especially for middle- and lower-income groups
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