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In this case, miRNAs can alter the gene expression of the CPT2 and CPT1 genes, which in turn affect mitochondrial function and fatty acid oxidation.[ref] Similarly, supplemental L-carnitine can affect inflammatory pathways through altering the expression of microRNAs that in turn decrease inflammatory cytokines.[ref] Genotype report: Carnitine Access this content: An active subscription is required to access this content

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Together, these findings support the need for further investigation into the pulmonary safety of paracetamol and ibuprofen in extremely preterm infants

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