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Its also possible to feel no obvious sensation at the time of injection, apart from maybe a warmth if given IV

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Useful metrics include body weight measured at consistent times, ideally morning after waking

Even though this effect may be mediated by the insulin receptor, experimental KO mice for the insulin receptor gene show a potent glucose lowering effect of IGF-1, indicative that the hypoglycaemic effect is also mediated, in part, by its own IGF-1R