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In the adrenal cortex, binding of ACTH by melanocortin 2 receptors initiates the production and release of GCs (cortisol in humans, and corticosterone in rodents)
A 2023 meta-analysis of 10 randomized, double-blind, placebo-controlled trials specifically examined the effect of vitamin C supplementation on the severity of cold symptoms
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Johnson W BW, Belsito DV
Thomson GT, Johnston JL, Baragar FD, Toole JW
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