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I was very clear that I was going to be a thyroid clinician, so the fact that I ended up working on these peptide hormones that had nothing to do with the thyroid that was disappointing, says Drucker, now a senior investigator at the Lunenfeld-Tanenbaum Research Institute at Sinai Health and a University Professor of medicine in U of Ts Temerty Faculty of Medicine
These bispecific molecules that antagonize GIPR and agonize GLP-1R pathways led to decreases in BW and improvements in metabolic parameters in obese mice and monkeys 34
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