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Lipofectamine 2000 (Invitrogen, Carlsbad, USA) was used to deliver plasmid constructs (2.2 g/6.0-cm Petri dish) into cells in accordance with the manufacturers instructions

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f-g , Single-cell clones were established from the polyclonal population, and GGT activity (f) (n = 3 technical replicates from 2 independent experiments) and cell numbers (g) (n = 6 technical replicates for Control or n = 4 technical replicates for Cys 2 -free + GSH from 2 independent experiments) for cells grown in control (208 M cystine

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