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[1] Persistently high B12 levels warrant medical investigation, as they may signal liver disease, kidney dysfunction, or certain haematological disorders

They received instructions to swallow it three times a day ( three capsules of 1 g each), after main meals, recording daily the quantity of capsules ingested on a specific form named Participants daily card. For each return visit to the site of research, aiming to receive, the participants answered to an adherence form, filled out by the pharmacist, immediately after medical appointment

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