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Abbreviations DPP-4: Dipeptidyl peptidase-4 GIP: Glucose-dependent insulinotropic polypeptide GLP-1: Glucagon-like peptide-1 IFG: Impaired fasting glucose IGT: Impaired glucose tolerance PYY: Peptide YY References Nauck M, Stckmann F, Ebert R, Creutzfeldt W (1986) Reduced incretin effect in type 2 (non-insulin-dependent) diabetes

doi: 10.1007/s40618-019-01034-5 10 FanYWeiFLangYLiuY

Five mice per group were used

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It stimulates the glucagon-like peptide-1 (GLP-1) receptors

Extracellular NAD(+) induces a rise in [Ca(2+)](i) in activated human monocytes via engagement of P2Y(1) and P2Y(11) receptors