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Its short sequence Gly-His-Lys binds Cu2+ ions with exceptional affinity through the histidine imidazole ring and the terminal amine, forming the characteristic blue complex
Allergic reactions, such as a skin rash, are rare
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Its once-weekly injection design gives it a clear advantage over older amylin analogs like pramlintide, which required multiple daily doses
It is not a routine prenatal supplementation method but rather a therapeutic intervention for specific needs
136, July 2015, pp
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