To obtain that information, the crystal structure of a truncated stabilised GLP-1 analogue bound to the receptor was solved using the Macromolecular Crystallography (MX) Microfocus beamline (I24)
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In addition, studies have shown that it also has a certain protective effect on reducing the incidence of cardiovascular disease in some high-risk groups
Am J Physiol Renal Physiol 301(2):F355F363 Day JW, Ottaway N, Patterson JT, Gelfanov V, Smiley D, Gidda J et al (2009) A new glucagon and GLP-1 co-agonist eliminates obesity in rodents