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2007 Aug;7(4):355-9

By organizing evidence primarily by CKD stage and metabolic phenotype, this review provides a clinically intuitive map of where renal evidence is concentrated and where it is lacking

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Meglitinides (Glinides) Examples: Repaglinide, Nateglinide Mechanism: Similar to sulfonylureas (stimulate insulin secretion), but short-acting taken before meals Side Effects: Hypoglycemia, weight gain Advantage: Useful for postprandial hyperglycemia 4

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Even small persistent elevations above this range trigger cascading metabolic consequences