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While GLP-1 medications alone have a low risk of hypoglycaemia, this risk increases when they are combined with insulin or sulfonylureas

In kidney studies, Glp1r/ knockout mice experienced worse nephritis and diabetic kidney damage

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However, this effect can also lead to gastrointestinal adverse effects, including nausea, vomiting, diarrhoea, and constipation , which are among the most commonly reported side effects

Ill see patients with underlying thyroid disease, underlying autoimmune disease, underlying neuroendocrine disease, Dr

Per the KFF 2025 Employer Health Benefits Survey, 43% of firms with 5,000-plus employees cover GLP-1s for weight loss (up from 28%), 30% of firms with 1,000 to 4,999, and 16% of firms with 200 to 999