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Additionally, AQP9 deficiency leads to impaired glycogen synthesis, evidenced by increased levels of phosphorylated glycogen synthase (GS)

Semiquinone state scavenges the free radicals by exchanging one electron from oxidized to the reduced state

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In line with these findings, PulseSight Therapeutics (formerly Eyevensys) is advancing the clinical development of PST-611, a transferrin-based non-viral gene therapy for the treatment of dry AMD and GA