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Effect of long-acting liraglutide QD on HR A 24-h time-averaged increase in mean placebo- and baseline-adjusted HR of 78 bpm was reported following liraglutide 1.2 and 1.8 mg QD (titrated in 0.6-mg weekly steps) using serial ECG monitoring at the end of the second and third weeks (after the seventh and final dose) of liraglutide (N = 51)

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A comprehensive analysis published in JAMA Internal Medicine confirmed these findings in real-world clinical settings, showing that tirzepatide consistently outperformed semaglutide for weight loss across different patient populations

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In Section C