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In 3-KO mice, these reductions were absent, reinforcing the idea that 3-AR plays a necessary role in regulating the response of brown adipose tissue to these agents [2]

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These substances are theorised to enhance hepatic fat metabolism and support liver function

Until such evidence emerges, clinical use should proceed with appropriate caution and recognition of the investigational nature of this promising but unproven therapeutic peptide

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Both compounds are proposed to influence metabolic pathways, albeit through distinct mechanisms