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Data availability about the pathophysiological processes involved in triggering NIHL has allowed researchers to use compounds, that could act as effective therapies, by targeting specific mechanisms such as the excess generation of free radicals and blood flow restriction to the cochlea
Abo Shama, Mokhtar R
& Tao, Y
Signalling-molecule effects: 1-methylnicotinamide is itself a signalling molecule
The REGAINE registration trials showed that 5% topical minoxidil produced a mean increase of 18.6 hairs per cm2 in the vertex area after 48 weeks
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