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Fat cells make estrogen, fueling the development and growth of estrogen receptor (ER)-positive breast cancer
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Additionally, the study found that weight gain after stopping was strongly associated with reinitiation, suggesting that many patients may need long-term therapy to maintain weight loss. The researchers concluded more studies are needed to explore how long-term health outcomes are tied to GLP-1 discontinuation and to assess how interventions financial barriers to the drugs and mitigate adverse events
Moving beyond food noise to drug noise, GLP-1s are quieting the roar of addiction. Reference: Metabolic medicines and addiction: what GLP-1 receptor agonists might add to substance use care by Fares Qeadan, 4 March 2026, BMJ
