In 2024, Sakuma et al., in Japan, carried out a clinical study to evaluate the effects of cysteine peptides, which included both reduced glutathione (GSH) and oxidized glutathione (GSSG), over 5 weeks
FDA banned it in late 2023 "Category 2: Substance with Safety Concerns" Why the FDA banned it: Potential immune reactions (immunogenicity) Manufacturing impurities in compounded versions Complete lack of human safety data Risk of contamination Legal status: NOT FDA-approved Illegal to compound in pharmacies Banned by WADA for athletes Possession not illegal (it's not a DEA scheduled substance) Sold online as "research chemical" 2
The localized application of PRP has shown promising results in reducing pain, improving function, and accelerating the recovery process in patients with patellar tendinopathy [16,17,18]
Improved circulation and reduced inflammation also suggest benefits for the gut-brain axi, possibly easing brain fog, mood swings, and cognitive fatigue that plague so many patients
Safety and efficacy of N-acetyl-cysteine for prophylaxis of ventilator-associated pneumonia: a randomized, double blind, placebo-controlled clinical trial
Rarely, individuals may experience more severe reactions, such as anaphylaxis, which requires immediate medical attention