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On the other hand, PCNA is essential for cell proliferation, and it interacts with various proteins in regulating the cell cycle, DNA replication, and DNA repair process (Mansilla et al., 2020)

9(1):e87191

PMID 39701638

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Diabetic neuropathy relief: strong evidence Alpha-lipoic acid (ALA) is one of the most well-researched supplements for diabetic peripheral neuropathy, a common complication of diabetes that can lead to nerve pain, tingling, numbness, and weakness in the limbs.19 Several clinical trials, particularly those involving intravenous ALA, have shown that doses of 600mg per day can reduce these symptoms over a matter of weeks.20 21 ALAs proposed benefit lies in its antioxidant activity

The doses may need to be increased to up to three times the recommended over-the-counter dosing