Those additions raise the risk of allergic or adverse reactions
The medication's effects on gastric motility and appetite require thoughtful planning to optimize tolerance and nutritional benefit
Despite the superior cardiorenal benefits of sodium/glucose cotransporter-2 inhibitors (SGLT-2i) and GLP-1RAs [75, 76], DPP-4i remained a common choice among these three classes of anti-diabetic agents, with more patients using DPP-4i than the other two [77]
Ethics declarations Funding VSS is supported by a Department of Medicine Eliot Phillipson Clinician-Scientist Training Program, a Banting and Best Diabetes Centre Postdoctoral Fellowship at the University of Toronto and a Canadian Institutes of Health Research (CIHR) Frederick Banting and Charles Best Canada Graduate Scholarships Doctoral Research Award
As Healio previously reported, findings from REWIND the first major CV outcomes trial for a diabetes therapy to include a large primary prevention population demonstrated that dulaglutide (Trulicity, Eli Lilly) reduced the composite risk for nonfatal myocardial infarction, nonfatal stroke and CV death by 12% compared with placebo, as well as renal benefits in participants assigned the drug
Journal of pharmacology & pharmacotherapeutics