In others, it may be provided through specialist weight management services
It was approved for type 2 diabetes in 2017 as Ozempic
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Regarding administration, the pill is taken once daily orally while the injection is administered once weekly via subcutaneous injection
Higher doses, such as 15 mg/d, have also been tested in short-term studies, though these did not significantly increase plasma spermidine levels owing to pre-systemic conversion into other polyamines, such as spermine (Reference Senekowitsch, Wietkamp and Grimm20)
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